针刺研究

2021, v.46(04) 342-347

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针刺辅助体外受精-胚胎移植临床研究的回顾与思考
Clinical studies on acupuncture assisting in vitro fertilization-embryo transfer: a review and thoughts

宋玙璠;胡茹楠;郑翠红;张明敏;
SONG Yu-fan;HU Ru-nan;ZHENG Cui-hong;ZHANG Ming-min;Institute of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology;

摘要(Abstract):

针灸应用于生殖领域历史悠久。近20年来,许多临床研究致力于探讨针刺在辅助生殖技术中的应用价值。但由于研究结果的不一致性,针刺辅助体外受精-胚胎移植(IVF-ET)的临床安全性和有效性一直备受争议。究其原因,与针灸临床试验缺乏规范化和标准化治疗方案密切相关。因此,本文回顾了1999年至2020年期间国际上发表的16项有关针刺辅助IVF-ET的代表性临床研究,归纳并总结了其分组设计、针刺方法(针刺时机、针刺频率、针刺穴位、针刺方式)和妊娠结局(妊娠率、临床妊娠率、持续妊娠率、活产率),并针对临床方案设计中的若干关键环节进行探讨,以期为今后的临床研究工作提供些许参考和帮助。
Acupuncture has a long history of application in the field of reproduction, and in the past 20 years, numerous clinical studies have been conducted to explore the value of acupuncture in assisted reproductive technology. However, due to inconsistent research findings, there are still controversies over the clinical safety and efficacy of acupuncture in assisting in vitro fertilization-embryo transfer(IVF-ET), which may be closely associated with lacking of standardized treatment regimen in clinical trials of acupuncture. For that reason, this article reviews 16 representative clinical trials of acupuncture assisting IVF-ET published worldwide in 1999—2020, summarizes the grouping design, acupuncture method(acupuncture timing, acupuncture frequency, acupoints, and acupuncture types), and pregnancy outcome(pregnancy rate, clinical pregnancy rate, ongoing pregnancy rate, and live birth rate), and discusses several key links in clinical protocol design, so as to provide references for future clinical research.

关键词(KeyWords): 针刺;体外受精-胚胎移植;临床研究
Acupuncture;In vitro fertilization-embryo transfer;Clinical research

Abstract:

Keywords:

基金项目(Foundation): 华中科技大学同济医学院附属同济医院临床医学研究启航项目(No.2019CR110)

作者(Author): 宋玙璠;胡茹楠;郑翠红;张明敏;
SONG Yu-fan;HU Ru-nan;ZHENG Cui-hong;ZHANG Ming-min;Institute of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology;

Email:

DOI: 10.13702/j.1000-0607.200427

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